High-resolution impedancometry and harmonic (Fourier) analysis of variable component of bioimpedance revealed rhythmic oscillations of urinary bladder bioimpedance at the Mayer wave, respiration, and heartbeat frequencies. The power values of the corresponding Mayer, respiratory, and cardiac peaks were calculated to assess circulation in the urinary bladder wall and its autonomic nervous control at various stages of infusion cystometry in intact rats and in the rats with preliminary formed infravesical obstruction (IVO). In intact rats, filling of the bladder with physiological saline diminished the power of the first (fundamental) cardiac peak attesting to a decrease of the blood flow in the bladder wall. Simultaneously, the power of low-frequency Mayer peak reflecting sympathetic activity increased, while the power of respiratory peak decreased supposedly reflecting abatement of the parasympathetic influences. Bladder voiding was accompanied by a decrease of Mayer peak and increase of the respiratory one. Prior to infusion cystometry, the intravesical pressure in IVO rats was elevated while the power of fundamental cardiac peak was below the control value. Filling the bladder in these rats was accompanied by further decrease of the cardiac peak reflecting still greater drop in blood supply. In control rats, voiding the bladder normalized the vesical circulation assessed by the cardiac peak, while in IVO rats this peak remained decreased. The reciprocal changes of Mayer and respiratory peaks observed during infusion cystometry in the norm were replaced by unidirectional decrease in the power of both peaks in IVO rats, which probably attest to disturbance of autonomic nervous control in the hypertrophic urinary bladder in these rats.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
V. I. Kirpatovsky, Yu. V. Kudryavtsev, I. S. Mudraya, et al., Byull. Eksp. Biol. Med., 147, No. 1, 108–112 (2009).
A. V. Nesterov, I. Yu. Gavrilov, L. Ya. Selector, et al., Byull. Eksp. Biol. Med., 150, No. 7, 31–37 (2010).
K. E. Andersson and A. Arner, Physiol. Rev., 84, No. 3, 935–986 (2004).
K. M. Azadzoi, Adv. Exp. Med. Biol., 539, Pt. A, 271–280 (2003).
K. M. Azadzoi, M. Pontari, J. Vlachiotis, and M. B. Siroky, J. Urol., 155, No. 4, 1459–1465 (1996).
K. M. Azadzoi, Z. M. Radisavljevic, T. Golabek, et al., J. Urol., 183, No. 1, 362–369 (2010).
R. T. Kershen, K. M. Azadzoi, and M. B. Siroky, J. Urol., 168, No. 1, 121–125 (2002).
S. Matsumoto, T. Hanai, N. Shimizu, H. Uemura, Hinyokika Kiyo, 54, No. 3, 179–184 (2008).
U. Mehnert, P. A. Knapp, N. Mueller, et al., Neurourol. Urodyn., 28, No. 4313–319 (2009).
A. Nergardh and A. C. Kinn, Scand. J. Urol. Nephrol., 17, No. 2, 153–157 (1983).
G. M. Pinggera, M. Mitterberger, L. Pallwein, et al., BJU Int., 101, No. 3, 319–324 (2008).
A. Schröder, P. Chichester, and B. A. Kogan, J. Urol., 165, No. 2, 640–646 (2001).
C. Sjogren, K. E. Andersson, S. Husted, J. Urol., 128, No. 6, 1368–1371 (1982).
D. J. Smith and C. R. Chapple, Neurourol. Urodyn., 34, 14–15 (1994).
L. C. Weaver, Am. J. Physiol., 248, No. 2, Pt. 2, R236–R240 (1985).
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 153, No. 4, pp. 422-426, April, 2012
Rights and permissions
About this article
Cite this article
Kirpatovsky, V.I., Mudraya, I.S., Revenko, S.V. et al. Assessment of Intramural Blood Flow and Neurogenic Control in Intact and Hypertrophic Urinary Bladder with Harmonic Analysis of Bioimpedance in Rats. Bull Exp Biol Med 153, 436–440 (2012). https://doi.org/10.1007/s10517-012-1734-4
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10517-012-1734-4