Experiments on the model of bilateral photothrombosis in the prefrontal cortex showed that antibodies to glutamate administered intranasally 1 h after ischemic damage to the brain cortex led to a decrease in glutamate content in the hippocampus and prefrontal cortex and had no effect on aspartate concentration in these structures of the brain.
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Translated from Byulleten’ Eksperimental’oi Biologii i Meditsiny, Vol. 153, No. 1, pp. 17-20, January, 2012
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Romanova, G.A., Kvashennikova, Y.N., Shakova, F.M. et al. Effect of Antibodies to Glutamate on the Content of Neurotransmitter Amino Acids in Brain Structures of Rats with Ischemic Damage to the Prefrontal Cortex. Bull Exp Biol Med 153, 13–15 (2012). https://doi.org/10.1007/s10517-012-1631-x
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DOI: https://doi.org/10.1007/s10517-012-1631-x