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Peroxisome Proliferator-Activated Receptors of Trophoblast Cells in Miscarriage

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Bulletin of Experimental Biology and Medicine Aims and scope

Comparative histological study of uterine curettage specimens in missed abortion in women with spontaneous and induced pregnancy and progressing spontaneous pregnancy revealed similar changes in the endometrium and placental villi. Immunohistochemical assay showed enhanced expression of PPARγ and increased proliferation index (Ki-67) in cells of the villous and extravillous trophoblasts in missed abortion.

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References

  1. Y. Barak, D. Liao, W. He, et al., Proc. Natl. Acad. Sci. USA., 99, No. 1, 303-308 (2002).

    Article  PubMed  CAS  Google Scholar 

  2. S. J. Bensinger and P. Tontonoz, Nature, Vol. 454, pp. 470-477 (2008).

  3. L. R. Dunn-Albanese, W. E. Ackerman, Y. Xie, et al., Am. J. Obstet. Gynecol., 190, No. 3, 809-816 (2004).

    Article  PubMed  CAS  Google Scholar 

  4. T. Fournier, K. Handschuh, V. Tsatsaris, and D. Evain-Brion, Placenta, 28, Suppl. A, S76-S81 (2007).

  5. T. Fournier, V. Tsatsaris, K. Handschuh, and D. Evain-Brion, Placenta, 28, Nos. 2-3, S65-S76 (2007).

    Article  Google Scholar 

  6. T. C. Li, M. Makris, M. Tomsu, et al., Human Reprod. Update, 8, No. 5, 463-481 (2002).

    Article  CAS  Google Scholar 

  7. K. W. Marvin, R. L. Eykholt, J. A. Keelan, et al., Placenta, 21, No. 4, 436-440 (2000).

    Article  PubMed  CAS  Google Scholar 

  8. L. Pavan, A. Tarrade, A. Hermouet, et al., Carcinogenesis, 24, No. 8, 1325-1336 (2003).

    Article  PubMed  CAS  Google Scholar 

  9. R. Rai and L. Regan, Lancet, 368, 601-611 (2006).

    Article  PubMed  Google Scholar 

  10. V. A. Rodie, A. Young, F. Jordan, et al., J. Soc. Gynecol. Invest., 12, No. 5, 320-329 (2005).

    Article  CAS  Google Scholar 

  11. W. T. Schaiff, Y. Barak, and Y. Sadovsky, Mol. Cell. Endocrinol., 249, Nos. 1-2, 10-15 (2006).

    Article  PubMed  CAS  Google Scholar 

  12. W. T. Schaiff, M. G. Carlson, S. D. Smith, et al., J. Clin. Endocrinol. Metab. 85, No. 10, 3874-3881 (2000).

    Article  PubMed  CAS  Google Scholar 

  13. A. Tarrade, K. Schoonjans, J. Guibourdenche, et al., Endocrinology, 142, No. 10, 4504-4514 (2001).

    Article  PubMed  CAS  Google Scholar 

  14. A. Tarrade, K. Schoonjans, L. Pavan, et al., J. Clin. Endocrinol. Metab. 86, No. 10, 5017-5024 (2001).

    Article  PubMed  CAS  Google Scholar 

  15. Q. Wang, H. Fujii, and G. T. Knipp, Placenta, 23, Nos. 8-9, 661-671 (2002).

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health Care and Social Development of the Russian Federation, Moscow, Russia

    N. V. Alexandrova, E. A. Dubova, O. R. Baev, A. I. Shchegolev & G. T. Sukhikh

Authors
  1. N. V. Alexandrova
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  2. E. A. Dubova
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  3. O. R. Baev
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  4. A. I. Shchegolev
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  5. G. T. Sukhikh
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Corresponding author

Correspondence to N. V. Alexandrova.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 152, No. 12, pp. 716-719, December, 2011

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Alexandrova, N.V., Dubova, E.A., Baev, O.R. et al. Peroxisome Proliferator-Activated Receptors of Trophoblast Cells in Miscarriage. Bull Exp Biol Med 152, 768–771 (2012). https://doi.org/10.1007/s10517-012-1627-6

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  • DOI: https://doi.org/10.1007/s10517-012-1627-6

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