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Subpopulation of Colorectal Adenocarcinoma Cells Co-Expressing CD133 and Cancer Stem Cells Markers of Other Tumors

  • Oncology
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Bulletin of Experimental Biology and Medicine Aims and scope

Co-expression of colorectal adenocarcinoma cancer stem cells marker CD133 and a set of surface molecules described in published reports as possible cancer stem cell markers of other solid tumors was analyzed by fl ow cytometry. Minor cell populations expressing CD29, CD34, CD90, and CD117 against the background of CD133 expression were detected in cancer cells suspensions from the patients with colorectal adenocarcinoma. Our fi ndings suggest that these markers can be used as additional markers of cancer stem cells of human colorectal adenocarcinoma.

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Authors and Affiliations

  1. V. N. Orekhovich Research Institute of Biomedical Chemistry, Russian Academy of Medical Sciences, Moscow, Russia

    A. M. Gisina, A. Yu. Lupatov, P. A. Karalkin & K. N. Yarygin

  2. Research Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow, Russia

    A. Yu. Lupatov & K. N. Yarygin

  3. P. A. Gertsen Moscow Research Oncological Institute, Federal Agency for High-Technological Medical Care, Moscow, Russia

    O. A. Mainovskaya, L. O. Petrov, D. V. Sidorov & G. A. Frank

Authors
  1. A. M. Gisina
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  2. A. Yu. Lupatov
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  3. P. A. Karalkin
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  4. O. A. Mainovskaya
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  5. L. O. Petrov
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  6. D. V. Sidorov
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  7. G. A. Frank
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  8. K. N. Yarygin
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Corresponding author

Correspondence to A. M. Gisina.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 152, No. 12, pp. 684-687, December, 2011

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Gisina, A.M., Lupatov, A.Y., Karalkin, P.A. et al. Subpopulation of Colorectal Adenocarcinoma Cells Co-Expressing CD133 and Cancer Stem Cells Markers of Other Tumors. Bull Exp Biol Med 152, 739–742 (2012). https://doi.org/10.1007/s10517-012-1620-0

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  • DOI: https://doi.org/10.1007/s10517-012-1620-0

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