Microcirculatory Disorders and Choice of Treatment Strategy for the Diabetic Foot Syndrome

Radioisotope method with ^99mTc pertechnetate is proposed for evaluation of the microcirculatory status of patients with the diabetic foot syndrome. The isotope (70-90 MBq) in 0.3-0.5 ml saline was injected subcutaneously into the interdigital spaces of the foot symmetrically on both sides. The severity of microcirculatory changes was evaluated by the rate of the radiopharmaceutical resorption using a computer-aided gamma counter. The data on the radiopharmaceutical half-resorption obtained by radioisotope study, serve as additional criteria for prediction of the disease course and choice of the treatment strategy for patients with the diabetic foot syndrome and diabetic gangrene of the lower limb.