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Disorders in the Secretory Cycle of Follicular Thyrocytes and Their Correction with Thyrotropic Hormone in Experimental Non-Thyroidal Illness Syndrome

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The inflence of LPS on the thyroid gland leads to more intensive synthesis and release of thyroglobulin into the follicle lumen and inhibition of its resorption and proteolysis, which reduces the production of thyroxine. Treatment with thyroid-stimulating hormone normalizing the secretory processes in the follicular thyrocytes is a pathogenetically justifi ed method for correction of non-thyroidal illness syndrome in acute endotoxicosis.

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Authors and Affiliations

  1. Institute of Human Morphology, Russian Academy of Medical Sciences, Moscow, Russia

    N. V. Yaglova

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  1. N. V. Yaglova
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Correspondence to N. V. Yaglova.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 152, No. 8, pp. 215-219, August, 2011

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Yaglova, N.V. Disorders in the Secretory Cycle of Follicular Thyrocytes and Their Correction with Thyrotropic Hormone in Experimental Non-Thyroidal Illness Syndrome. Bull Exp Biol Med 152, 253–257 (2011). https://doi.org/10.1007/s10517-011-1501-y

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  • DOI: https://doi.org/10.1007/s10517-011-1501-y

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