Skip to main content
Log in

Effect of chelating agents and stress factors on zinc content in Paneth cells and prostate gland cells

  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

The effects of chelating agents dithizone and sodium diethyldithiocarbamate on zinc content in Paneth cells and prostate gland cells were studied on rats preliminary exposed to stress factors (exercise and immobilization). Dithizone induced irreversible triphasic and sodium diethyldithiocarbamate reversible biphasic changes in zinc metabolism in cells. Preliminary stress potentiated the damaging effect of dithizone.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. A. P. Avtsyn, A. A. Zhavoronkov, M. A. Rish, and L. S. Strochkova, Human Microelementoses: Etiology, Classification, Organopathology [in Russian], Moscow (1991).

  2. E. D. Goldberg, V. A. Eshchenko, and V. D. Bovt, Diabetes. Etiological Factors [in Russian], Tomsk (1993).

  3. J. V. Eshchenko, Fiziolohichniy Zh., 55, 72–78 (2009).

    Google Scholar 

  4. J. V. Eshchenko, Stres i Klitynny Metabolizm Metaliv [in Ukrainian], Zaporozhye (2010).

  5. V. V. Novitskiy, I. O. Naslednikova, and O. I. Urazova, Byull. Eksp. Biol. Med., 136, No. 16, 390–393 (2003).

    Google Scholar 

  6. V. V. Novitskiy and O. I. Urazova, Uspekhi Fiziol. Nauk, 35, No. 1, 43–52 (2004).

    Google Scholar 

  7. T. Ayabe, D. P. Satchell, P. Pesendorfer, et al., J. Biol. Chem., 277, No. 7, 5219–5228 (2002).

    Article  PubMed  CAS  Google Scholar 

  8. T. Ayabe, D. P. Satchell, C. L. Wilson, et al., Nat. Immunol., 1, No. 2, 113–118 (2000).

    Article  PubMed  CAS  Google Scholar 

  9. R. I. Lehrer and T. Ganz, Curr. Opin. Immunol., 14, No.1, 96–102 (2002).

  10. W. Maret, J. Nutr., 130, 5S Suppl., 1455S–1458S (2000).

    PubMed  CAS  Google Scholar 

  11. H. Tanabe, J. Yuan, M. M. Zarogoza, et al., Infect. Immun., 72, No. 3, 1470–1478 (2004).

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to O. I. Urazova.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 152, No. 8, pp. 140–143, August, 2011.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Novitskiy, V.V., Eshchenko, J.V., Bovt, V.D. et al. Effect of chelating agents and stress factors on zinc content in Paneth cells and prostate gland cells. Bull Exp Biol Med 152, 180–183 (2011). https://doi.org/10.1007/s10517-011-1482-x

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10517-011-1482-x

Keywords

Navigation