We studied changes in the autonomic balance of heart regulation (by the parameters of heart rate variability) in non-pregnant female rats and rats on the days 10–11 of pregnancy on the next day after stress provoked by acute hypobaric hypoxia, intermittent normobaric hypoxia, or immobilization. The same parameters were assessed in 36-day-old offspring. In nonpregnant rats, the intermittent hypoxia resulted in a shift of the autonomic balance of heart regulation towards activation of the parasympathetic nervous system; in pregnant females, immobilization led to a shift of the autonomic balance towards the sympathetic nervous system. In the offspring, the changes also depended on the type of stress.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 151, No. 6, pp. 611–614, June 2011
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Dunaeva, T.Y., Maslova, M.V., Trofimova, L.K. et al. Comparative Analysis of the Effects of Various Stress Factors at the Stage of Early Organogenesis on Heart Rate Variability in Pregnant Female Rats and Their Offspring. Bull Exp Biol Med 151, 667–670 (2011). https://doi.org/10.1007/s10517-011-1411-z
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DOI: https://doi.org/10.1007/s10517-011-1411-z