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Comparative Characteristics of Platelet Lysates from Different Donors

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Bulletin of Experimental Biology and Medicine Aims and scope

We studied the effect of platelet lysates from different donors on fibroblast growth in culture. In most samples (40 of 50), the growth-stimulating characteristics were greater than in 10% FCS, but every ninth sample exhibited low mitogenic activity. A weak dependence between platelet concentration and total protein content was noted, but no correlation was found between these parameters and fibroblast growth in culture.

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Authors and Affiliations

  1. Trans-Tekhnologii Company, St. Petersburg, Russia

    N. V. Kalmykova, E. V. Skorobogataya, M. A. Berestovoy, P. V. Kruglyakov & D. G. Polintsev

  2. I. P. Pavlov St. Petersburg State Medical University, R. M. Gorbacheva Institute of Children Hematology and Transplantology, St. Petersburg, Russia

    M. A. Estrina & B. V. Afanasiev

Authors
  1. N. V. Kalmykova
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  2. E. V. Skorobogataya
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  3. M. A. Berestovoy
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  4. P. V. Kruglyakov
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  5. M. A. Estrina
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  6. B. V. Afanasiev
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  7. D. G. Polintsev
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Corresponding author

Correspondence to N. V. Kalmykova.

Additional information

Translated from Kletochnye Tekhnologii v Biologii i Meditsine, No. 2, pp. 114–117, April, 2011

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Kalmykova, N.V., Skorobogataya, E.V., Berestovoy, M.A. et al. Comparative Characteristics of Platelet Lysates from Different Donors. Bull Exp Biol Med 151, 547 (2011). https://doi.org/10.1007/s10517-011-1378-9

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  • DOI: https://doi.org/10.1007/s10517-011-1378-9

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