Animals were immunized with transmissible gastroenteritis virus conjugated with gold nanoparticles. The resultant antibodies had a higher titer than antibodies produced in response to native virus. Immunization with the antigen-colloidal gold complex led to a significant increase of the peritoneal macrophages respiratory activity and of plasma IFN-γ level in immunized animals.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 151, No. 4, pp. 418–421, April, 2011
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Staroverov, S.A., Vidyasheva, I.V., Gabalov, K.P. et al. Immunostimulatory Effect of Gold Nanoparticles Conjugated with Transmissible Gastroenteritis Virus. Bull Exp Biol Med 151, 436 (2011). https://doi.org/10.1007/s10517-011-1350-8
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DOI: https://doi.org/10.1007/s10517-011-1350-8