We present the results of immunoenzyme detection of inhibin B in blood serum of patients with adult-type granulosa cell tumors of the ovary. Blood concentration of inhibin B at the end of menstrual cycle in patients with tumor relapse was significantly higher than in patients during remission and in virtually healthy women. The increase in inhibin B concentration preceded clinical manifestation of the disease relapse by 2–13 months, which demonstrates high diagnostic sensitivity of this marker and suggests that it can be recommended for the use in diagnostics and monitoring of granulosa cell tumors of the ovaries.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 150, No. 11, pp. 567–570, November, 2010
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Lyubimova, N.V., Beyshembaev, A.M., Kushlinskiy, D.N. et al. Granulosa Cell Tumors of the Ovary and Inhibin B. Bull Exp Biol Med 150, 635–638 (2011). https://doi.org/10.1007/s10517-011-1209-z
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DOI: https://doi.org/10.1007/s10517-011-1209-z