Changes in liver structure in experimental CCl4-induced hepatitis depend on the phase of the circumannual cycle. Pronounced disorders in the liver with a model of toxic hepatitis were observed in winter and fall and minor changes were recorded in summer. In spring, the liver was characterized by higher adaptation and compensatory potential, its structural status spontaneously returned to normal on day 4 after the last injection of CCl4.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 149, No. 5, pp. 581–583, May, 2010
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Levitskii, E.F., Shilkina, E.S. & Mustafina, L.R. Changes in Liver Structure in Experimental CCl4-Induced Hepatitis during Different Phases of Circumannual Cycle. Bull Exp Biol Med 149, 647–649 (2010). https://doi.org/10.1007/s10517-010-1015-z
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DOI: https://doi.org/10.1007/s10517-010-1015-z