An increase of adhesion and aggregation functions of platelets in vivo and in vitro was detected in 5-6-year-old children with scoliosis. These disorders were caused by hyperproduction of von Willebrand’s factor in the vascular wall and intensification of thromboxane production in blood platelets. Activation of thromboxane formation is the main cause of platelet hyperactivity in children with scoliosis. Correction of platelet hemostasis may include pathogenetically substantiated complex of therapeutic exercises, swimming, and massage.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 149, No. 5, pp. 579–580, May, 2010
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Medvedev, I.N., Lapshina, E.V. & Zavalishina, S.Y. Activity of Platelet Hemostasis in Children with Spinal Deformities. Bull Exp Biol Med 149, 645–646 (2010). https://doi.org/10.1007/s10517-010-1014-0
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DOI: https://doi.org/10.1007/s10517-010-1014-0