We studied the effect of preliminary loading of peritoneal macrophages with silicium dioxide on in vitro viability, phagocytosis of BCG strain mycobacteria, and the capability to destroy the phagocytosed mycobacterium tuberculosis. It was shown that preliminary loading of macrophages with silicium dioxide did not reduce their viability and stimulated phagocytosis of BCG strain mycobacteria, but reduced their antibacterial activity.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
E. D. Goldberg, A. M. Dygai, and V. P. Shakhov, Methods of Tissue Culture in Hematology [in Russian], Tomsk (1992).
N. K. Zenkov, V. Z. Lankin, and E. B. Men’shikova, Oxidative Stress Moscow (2001).
M. S. Novikova, O. V. Potapova, and V. A. Skurupy, Byull. Eksp. Biol. Med., 146, No. 9, 250–253 (2008).
V. A. Skurupy, Tuberculous Granulomatosis. Cytophysiology and Targeted Therapy [in Russian], Moscow (2007).
V. A. Shkurupii, S. A. Arkhipov, A. V. Troitskii, et al., Kletoch. Tekhnol. Biol. Med., No. 4, 197–201 (2009).
V. A. Shkurupii, Yu. N. Kurunov, and N. N. Yakovchenko, Lysosomotropism: Problems of Cell Physiology and Medicine [in Russian], Novosibirsk (1999).
V. Castranova, L. J. Huffman, D. J. Judy, et al., Environ. Health Perspect.106, No. 5, 1165–1169 (1998).
A. Dubaniewicz and A. Hoppe, Rosz. Akad. Med. Bialymst., 49, 252–255 (2004).
R. M. Gilberti, G. N. Joshi, and D. A. Knecht, Am. J. Respir. Cell Mol. Biol., 39, No. 5, 619–627 (2008).
E. M. Mulenga, H. B. Miller, T. Sinkala, et al., Int. J. Occup. Environ. Health.,11, No. 3, 259–262 (2005).
F. Rost, Fluorescence microscopy, Cambridge (1995).
R. Smithwick, M. R. Bigbie, R. B. Ferguson, et al., J. Clin. Microbiol., 33, No. 10, 2763–2764 (1995).
J. M. Waternaude, R. I. Ehrlich, G. J. Churchyard, et al., Occup. Environ. Med., 2006. 63, No. 3, 187–192 (2004).
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Kletochnye Tehnologii v Biologii i Medicine, No. 2, pp. 103–105, April, 2010
Rights and permissions
About this article
Cite this article
Arkhipov, S.A., Shkurupy, V.A. & Bugrimova, Y.S. Effect of Preliminary Load of Macrophages with Silicium Dioxide on Phagocytosis of BCG Strain Micobacteria by Macrophages and Antimicrobial Activity. Bull Exp Biol Med 149, 534–536 (2010). https://doi.org/10.1007/s10517-010-0986-0
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10517-010-0986-0