We compared physiological activity of synthetic complexes from angiotensin IV and functionally different proteins (transport protein, bovine serum albumin; and neurospecific Ca2+-binding protein, S100b) as model analogues of endogenous protein-peptide complexes. Physiological activity of angiotensin IV was specifically modified by these proteins. Our results suggest that complexes of angiotensin IV with bovine serum albumin and S100b are strong factors for the integration of central and peripheral functions at the homeostatic and behavioral level.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
V. S. Varlakov, A. P. Shcherbina, A. V. Shvadchenko, et al., Automatic Device for Studying the Operant Behavior of Animals [in Russian], Investor’s Certificate SU No. 1813382 A 1 (1992).
A. V. Kotov, S. M. Tolpygo, E. I. Pevtsova, and M. F. Obukhova, Vestn. Ros. Akad. Med. Nauk, No. 4, 36–43 (2001).
A. V. Kotov, S. M. Tolpygo, E. I. Pevtsova, and M. F. Obukhova, Ros. Fiziol. Zh., 88, No. 6, 686–698 (2002).
A. V. Kotov, S. M. Tolpygo, E. I. Pevtsova, and M. F. Obukhova, Byull. Eksp. Biol. Med., 146, No. 8, 135–137 (2008).
S. Y. Chai, R. Fernando, G. Peck, et al., Cell. Mol. Life Sci., 61, No. 21, 2728–2737 (2004).
D. Daniels, D. K. Yee, L. F. Faulconbridge, and S. J. Fluharty, Endocrinology, 146, No. 12, 5552–5560 (2005).
M. de Casparo, K. J. Catt, T. Inagami, et al., Pharmacol. Rev., 52, No. 3, 415–472 (2000).
L. Hunyady and K. J. Catt, Mol. Endocrinol., 20, No. 5, 953–970 (2006).
M. Kurdi, W. C. De Mello, and G. W. Booz, Int. J. Biochem. Cell Biol., 37, No. 7, 1357–1367 (2005).
L. Loufrani, D. Henrion, D. Chansel, et al., J. Pharmacol. Exp. Ther., 291, No. 2, 583–588 (1999).
T. Mustafa, J. H. Lee, S. Y. Chai, et al., J. Renin Angiotensin Aldosterone Syst., 2, No. 4, 205–210 (2001).
M. R. Rosen and I. S. Cohen, J. Physiol., 570, Pt. 2, 209–218 (2006).
M. Ruiz-Ortega, V. Esteban, and J. Egido, Trends Cardiovasc. Med., 17, No. 1, 19–25 (2007).
B. Stragier, D. De Bundel, S. Sarre, et al., Heart Fail. Rev., 13, No. 3, 321–337 (2008).
J. W. Wright, B. J. Yamamoto, and J. W. Harding, Prog. Neurobiol., 84, No. 2, 157–181 (2008).
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 148, No. 11, pp. 491–494, November, 2009
Rights and permissions
About this article
Cite this article
Pevtsova, E.I., Tolpygo, S.M., Obukhova, M.F. et al. Complexes of Angiotensin IV with Functionally Different Proteins in the Regulation of Drinking Behavior and Hemodynamics in Rats. Bull Exp Biol Med 148, 738–741 (2009). https://doi.org/10.1007/s10517-010-0805-7
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10517-010-0805-7