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Effect of Ultralow Doses of Antibodies to S-100 Protein in Animals with Impaired Cognitive Function and Disturbed Emotional and Neurological Status under Conditions of Experimental Alzheimer Disease

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Course administration of ultralow doses of antibodies to S-100 protein restores cognitive functions and neurological status, improves emotional state, and reduces anxiety in animals with modeled Alzheimer disease based on cholinergic system defi ciency caused by subchronic treatment with scopolamine.

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References

  1. T. A. Voronina and R. U. Ostrovskaya, Manual on Experimental (Preclinical) Study of New harmacological Substances. Ed. R. U. Khabriev [in Russian], Moscow (2005), pp. 308-320.

  2. I. V. Gannushkina, Zh. Nevrol. Psikhiatr., No. 1, 14-18 (1996).

  3. X. Barril, S. G. Kalko, M. Orozco, and F. J. Luque, Mini Rev. Med. Chem., 2, No. 1, 27-36 (2002).

    Article  CAS  PubMed  Google Scholar 

  4. P. Camps and D. Munos-Torrero, Ibid., pp. 11-25.

  5. J. J. Claus, C. Ludwig, E. Mohr, et al., Neurology, 41, No. 4, 570-574 (1991).

    CAS  PubMed  Google Scholar 

  6. A. H. Gouliaev and A. Senning, Brain Res. Brain Res. Rev., 19, No. 2, 180-222 (1994).

    Article  CAS  PubMed  Google Scholar 

  7. S. Рellow and S. E. File, Pharmacol. Biochem. Behav., 24, No. 3, 525-529 (1986).

    Article  Google Scholar 

  8. M. Pomponi, E. Giacobini, and M. Brufani, Aging. (Milano)., 2, No. 2, 125-153 (1990).

    CAS  Google Scholar 

  9. T. A.Voronina, Alzheimer Disease: Therapeutic Strategies. Eds. E.Giacobini et al. Boston (1994).

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 148, Suppl. 1, pp. 174-176, September, 2009

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Voronina, T.A., Belopol’skaya, M.V., Kheyfets, I.A. et al. Effect of Ultralow Doses of Antibodies to S-100 Protein in Animals with Impaired Cognitive Function and Disturbed Emotional and Neurological Status under Conditions of Experimental Alzheimer Disease. Bull Exp Biol Med 148, 533–535 (2009). https://doi.org/10.1007/s10517-010-0757-y

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  • DOI: https://doi.org/10.1007/s10517-010-0757-y

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