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Erythrocyte Membrane Surface after Calibrated Electroporation: Visualization by Atomic Force Microscopy

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Atomic force microscopy was used for examination of the surface of human erythrocyte membrane after calibrated electroporation and application of pharmacological agents. Three-order surface inhomogeneities were revealed with various spectral windows of Fourier transform to elaborate the quantitative criteria to assess the state of membrane surface. The size of structural alterations induced in the membranes by electroporation was 100-300 nm, which is comparable to the size of membrane matrix.

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Authors and Affiliations

  1. Research Institute of General Resuscitaion Russian Academy of Medical Sciences, Moscow, Russia

    A. M. Chernysh & E. K. Kozlova

  2. I. M. Sechenov Moscow Medical Academy, Moscow, Russia

    V. V. Moroz, P. Yu. Borshagovskaya, U. A. Bliznuk & R. M. Rysaeva

Authors
  1. A. M. Chernysh
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  2. E. K. Kozlova
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  3. V. V. Moroz
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  4. P. Yu. Borshagovskaya
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  5. U. A. Bliznuk
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  6. R. M. Rysaeva
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Corresponding author

Correspondence to A. M. Chernysh.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 148, No. 9, pp. 347-352, September, 2009

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Chernysh, A.M., Kozlova, E.K., Moroz, V.V. et al. Erythrocyte Membrane Surface after Calibrated Electroporation: Visualization by Atomic Force Microscopy. Bull Exp Biol Med 148, 455–460 (2009). https://doi.org/10.1007/s10517-010-0735-4

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  • DOI: https://doi.org/10.1007/s10517-010-0735-4

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