Skip to main content
SpringerLink
Log in

Clinical and Immunological Efficiency of Anaferon (Pediatric Formulation) in Calicivirus Infection in Children

  • Ultralow Doses
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Therapy with anaferon (pediatric formulation) during the acute period of calicivirus infection shortened the duration of the main symptoms of the disease and period of virus release. Changes in the immunological status included increased production of IgA and IgM and activation of IFN-α synthesis.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. B. Ya Vasil’ev, R. I. Vasil’eva, and Yu. V. Lobzin, Acute Intestinal Diseases. Rotaviruses and Rotavirus Infection [in Russian], St. Petersburg (2000).

  2. A. V. Gorelov, Ros. Pediatr. Zh., No. 2, 58–60 (1998).

  3. N. M. Gracheva, A. A. Avakov, T. A. Blokhina, et al., Lechashchii Vrach, No. 3, 48–51 (1998).

  4. F. I. Ershov, A. N. Narovlyanskii, and M. V. Mezentseva, Tsitokiiny i Vospalenie, 3, No. 1, 3–6 (2004).

    Google Scholar 

  5. S. A. Ketlinskii and N. M. Kalinina, Immunology for Physicians [in Russian], St. Petersburg (1998).

  6. D. K. Novikov and V. I. Novikova, Evaluation of the Immune Status [in Russian], Moscow Vitebsk (1996).

  7. A. A. Novokshonov, Lectures on Pediatrics, Vol. 1 [in Russian], Moscow (2001), pp. 88–104.

  8. V. F. Uchaikin, Acute Intestinal Infections in Children [in Russian], Moscow (2005).

  9. V. F. Uchaikin, Detskie Infektsii, No. 1, 10–12 (2003).

  10. J. M. Cowden, Br. Med. J. 324, No. 7332, 249–250 (2002).

    Article  Google Scholar 

  11. R. I. Glass, J. Noel, T. Ando, et al., J. Infect. Dis., 181, Suppl. 2, S254-S261 (2000).

    Article  Google Scholar 

  12. B. A. Lopman, M. H. Reacher, J. Van Duijnhoven, et al., Emerg. Infect. Dis., 9, No. 1, 90–96 (2003).

    PubMed  Google Scholar 

  13. G. С. Sen, Annu. Rev. Microbiol., 55, 255–281 (2001).

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of Children Infections, Federal Agency for Health Care and Social Development, St. Petersburg, Russia

    O. V. Tikhomirova, I. V. Razd’yakonova, M. K. Bekhtereva, G. F. Zheleznikova & N. E. Monakhova

  2. Institute of Influenza, Russian Academy of Medical Sciences, St. Petersburg, Russia

    A. K. Sirotkin

Authors
  1. O. V. Tikhomirova
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. I. V. Razd’yakonova
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. M. K. Bekhtereva
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. G. F. Zheleznikova
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. N. E. Monakhova
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. A. K. Sirotkin
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 148, Suppl. 1, pp. 35–38, August, 2009

Rights and permissions

Reprints and permissions

About this article

Cite this article

Tikhomirova, O.V., Razd’yakonova, I.V., Bekhtereva, M.K. et al. Clinical and Immunological Efficiency of Anaferon (Pediatric Formulation) in Calicivirus Infection in Children. Bull Exp Biol Med 148, 287–290 (2009). https://doi.org/10.1007/s10517-009-0701-1

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10517-009-0701-1

Key Words

Search

Navigation