Phagocytic activity of alveolar macrophages isolated from rat bronchoalveolar lavage fluid was studied during their reaction with multilamellar liposomes containing biene (a complex of unsaturated fatty acids). Liposomes with incorporated biene significantly stimulated phagocytic activity of freshly isolated macrophages and primary culture of these cells (judging from the increase in phagocytic index and phagocytic number). A quantitative relationship between the phagocytic number and phagocytic index, on the one hand, and the concentration of liposomal biene, on the other, was detected. The effects of liposomes containing incorporated biene, liposomes of similar composition without biene, and pure biene substance on cell suspension were compared.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
I. M. Bushmakina, E. V. Skorinko, M. A. Martynova, and S. V. Konev, Doklady Natsional’n. Akad. Nauk Belarusi, 48, No. 2, 79–81 (2004).
I. V. Gamel’, P. T. Petrov, and V. M. Tsarenkov, Novosti Farmatsii, No. 1, 38–40 (1998).
L. N. Dedova and I. N. Fyodorova, Belarussk. Med. Zh., 15, No. 1, 46–49 (2006).
L. N. Dedova, I. N. Fyodorova, P. T. Petrov, Dostizhen. Med. Nauki Belarusi, No. 9, 237–238 (2004).
E. M. Lobanova and A. D. Taganovich, Belarussk. Med. Zh., 11, No. 1, 66–68 (2005).
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 148, No. 8, pp. 170–172, August, 2009
Rights and permissions
About this article
Cite this article
Bushmakina, I.M., Drozdova, N.I. & Martynova, M.A. Phagocytic Activity of Alveolar Macrophages in the Presence of Liposomal “Biene”. Bull Exp Biol Med 148, 204 (2009). https://doi.org/10.1007/s10517-009-0666-0
Received:
Published:
DOI: https://doi.org/10.1007/s10517-009-0666-0