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Norepinephrine Content in the Hypothalamus and Medulla Oblongata of ISIAH Rats is Regulated by Several Genetic Loci

  • Genetics
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Five genetic loci regulating epinephrine content in rat hypothalamus and two loci in the medulla oblongata were identified using polymorphic microsatellite DNA markers. Allele polymorphism of these loci determines the differences between norepinephrine levels in brain compartments of hypertensive ISIAH and normotensive WAG rats. The interactions between the detected epinephrine-regulating loci are additive.

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Authors and Affiliations

  1. Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia

    O. E. Redina, S. E. Smolenskaya & and A. L. Markel

  2. Institute of Physiology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia

    G. S. Jacobson

Authors
  1. O. E. Redina
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  2. S. E. Smolenskaya
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  3. G. S. Jacobson
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  4. and A. L. Markel
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Corresponding author

Correspondence to O. E. Redina.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 148, No. 8, pp. 191–194, August, 2009

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Redina, O.E., Smolenskaya, S.E., Jacobson, G.S. et al. Norepinephrine Content in the Hypothalamus and Medulla Oblongata of ISIAH Rats is Regulated by Several Genetic Loci. Bull Exp Biol Med 148, 223–226 (2009). https://doi.org/10.1007/s10517-009-0663-3

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  • DOI: https://doi.org/10.1007/s10517-009-0663-3

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