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Molecular Markers of Tumors

  • Oncology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

The main biologically significant molecular markers of human tumors are discussed on the basis of modern published data and author’s findings of many-year studies: steroid hormone receptors, growth factors and underlying signal proteins, tumor-associated proteases, and angiogenesis markers. Methodological aspects, progress in preclinical studies, international recommendations on the use of these parameters for prediction of the disease course and prescription of effective therapy are analyzed. Latest data on the potentialities and limitations of modern highly productive technologies (microchips) as an alternative to studies of individual molecular markers are presented.

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Authors and Affiliations

  1. N. N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russia

    N. E. Kushlinsky, E. S. Gershtein, L. K. Ovchinnikova & M. A. Digaeva

Authors
  1. N. E. Kushlinsky
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  2. E. S. Gershtein
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  3. L. K. Ovchinnikova
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  4. M. A. Digaeva
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Corresponding author

Correspondence to N. E. Kushlinsky.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 148, No. 8, pp. 199–208, August, 2009

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Kushlinsky, N.E., Gershtein, E.S., Ovchinnikova, L.K. et al. Molecular Markers of Tumors. Bull Exp Biol Med 148, 230 (2009). https://doi.org/10.1007/s10517-009-0661-5

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  • DOI: https://doi.org/10.1007/s10517-009-0661-5

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