Functional activity of the thyroid gland is reduced in Wistar rats with acute experimental endotoxicosis developing in response to sublethal dose of LPS and paralleled by polarization of the immune response by the Th-1 type. This decrease does not depend on the level of thyrotropic hormone and correlates with the production of IL-2 and IFN-γ.
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Translated from Byulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 147, No. 6, pp. 635-638, June, 2009
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Yaglova, N.V. Relationship between Functional Activity of the Thyroid Gland and Levels of Proinflammatory and Immunoregulatory Cytokines in Acute Experimental Endotoxicosis. Bull Exp Biol Med 147, 698–700 (2009). https://doi.org/10.1007/s10517-009-0603-2
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DOI: https://doi.org/10.1007/s10517-009-0603-2