Skip to main content

Advertisement

Log in

Expression of Growth Factors in Endotheliocytes in Vascular Malformations

  • Morphology and Pathomorphology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

The expression of growth factors and proliferation of endotheliocytes in vascular malformations were studied by immunohistochemical methods. The detected specific features of growth factor expression in the endothelium of venous and arteriovenous malformations seem to reflect the differences in the pathogenesis of these formations. High proliferative activity of the endothelium in angiodysplasias of both types can underlie the disease relapsing.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. A. P. Milovanov, Pathomorphology of Angiodysplasias of the Limbs [in Russian], Moscow (1978).

  2. O. D. Mishnyov and A. I. Shchyogolev, Angiodysplasias (Congenital Vascular Malformations) [in Russian], Moscow (2008), pp. 34–53.

  3. Y. G. Chen and J. Massague, J. Biol. Chem., 274, No. 6, 3672–3677 (1999).

    Article  PubMed  CAS  Google Scholar 

  4. S. Hiratsuka, Y. Maru, A. Okada, et al., Cancer Res., 61, No. 3, 1207–1213 (2001).

    PubMed  CAS  Google Scholar 

  5. M. J. Karkkainen, P. Haiko, K. Sainio, et al., Nat. Immunol., 5, No. 1, 74–80 (2004).

    Article  PubMed  CAS  Google Scholar 

  6. T. Koizumi, T. Shiraishi, N. Hagihara, et al., Neurosurgery, 50, No. 1, 117–124 (2002).

    Article  PubMed  Google Scholar 

  7. L. B. Meijer-Jorna, C. M. van der Loos, O. J. de Boer, et al., J. Clin. Pathol., 60, No. 7, 798–803 (2007).

    Article  PubMed  Google Scholar 

  8. M. Murakami, L. T. Nguyen, Z. W. Zhang, et al., J. Clin. Invest., 118, No. 10, 3355–3366 (2008).

    Article  PubMed  CAS  Google Scholar 

  9. T. Nakamura, Y. Mochizuki, H. Kanetaki, and S. Karda, Biochem. Biophys. Res. Commun., 289, No. 4, 801–806 (2001).

    Article  PubMed  CAS  Google Scholar 

  10. T. J. Poole, E. B. Finkelstein, and C. M. Cox, Dev. Dyn., 220, No. 1, 1–17 (2001).

    Article  PubMed  CAS  Google Scholar 

  11. M. Presta, P. Dell’Era, S. Mitola, et al., Cytokine Growth Factor Rev., 16, No. 6, 159–178 (2005).

    Article  PubMed  CAS  Google Scholar 

  12. U. Sure, N. Butz, J. Schlegel, et al., J. Neurosurg., 94, No. 6, 972–977 (2001).

    Article  PubMed  CAS  Google Scholar 

  13. J. C. Tille and M. S. Pepper, Arterioscler. Thromb. Vasc. Biol., 24, No. 9, 1578–1590 (2004).

    Article  PubMed  CAS  Google Scholar 

  14. W. Tirakotai, B. Liu-Guan, H. Bertalanffy, et al., Chinese Med. J., 117,1815–1820 (2004).

    CAS  Google Scholar 

  15. R. Uranishi, N. I. Baev, P. Y. Ng, et al., Neurosurgery, 48, No. 2, 359–367 (2001).

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to K. A. Pavlov.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 147, No. 3, pp. 341–345, March, 2009

Rights and permissions

Reprints and permissions

About this article

Cite this article

Pavlov, K.A., Dubova, E.A., Shchyogolev, A.I. et al. Expression of Growth Factors in Endotheliocytes in Vascular Malformations. Bull Exp Biol Med 147, 366–370 (2009). https://doi.org/10.1007/s10517-009-0510-6

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10517-009-0510-6

Key Words

Navigation