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Studying the Photoprotective Activity of a New Class of Heteroaromatic Antioxidants

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Bulletin of Experimental Biology and Medicine Aims and scope

Photoprotective activity of heteroaromatic compounds (derivatives of 3-hydroxypyridine, amino-6-hydroxybenzothiazole, and 5-hydroxybenzimidazole) was studied in the system of UV-induced cardiolipin peroxidation. Although all three compounds had the antioxidant effect during free radical oxidation of luminol, only derivatives of amino-6-hydroxybenzothiazole and 5-hydroxybenzimidazole inhibited the process of UV-induced lipid peroxidation. The 3-hydroxypyridine derivative did not inhibit UV-induced cardiolipin peroxidation, which was probably related to degradation of this compound under the influence of UV light and formation of degradation products that cannot inhibit free radical processes.

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References

  1. A. E. Dontsov, N. L. Sakina, and M. A. Ostrovsky, Sensornye Sistemy, 20, No. 4, 265-269 (2006).

    Google Scholar 

  2. G. I. Klebanov, Yu. O. Teselkin, I. V. Babenkova, et al., Vestn. Ros. Akad. Med. Nauk, No. 2, 15-22 (1999).

  3. L. D. Smirnov, Chemical and Biological Kinetics. New Horizonts [in Russian], Moscow (2005), pp. 102-129.

  4. L. D. Smirnov, L. G. Stolyarova, O. G. Kesarev, and V. P. Zhestkov, Ros. Khim. Zh., No. 6, 114-119 (1998).

  5. Yu. O. Teselkin, I. V. Babenkov, O. B. Lyubitskii, et al., Vopr. Med. Khim., 43, 87-92 (1997).

    CAS  Google Scholar 

  6. M. Porembska-Budny, N. L. Sakina, K. B. Stepien, et al., Biochim. Biophys. Acta, 116, No. 1, 11-16 (1992).

    Google Scholar 

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Authors and Affiliations

  1. N. M. Emanuel’ Institute of Biochemical Physics, Russian Academy of Sciences, Moscow, Russia

    N. L. Sakina, A. M. Golubkov, L. D. Smirnov, M. A. Ostrovsky & A. E. Dontsov

Authors
  1. N. L. Sakina
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  2. A. M. Golubkov
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  3. L. D. Smirnov
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  4. M. A. Ostrovsky
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  5. A. E. Dontsov
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Corresponding author

Correspondence to N. L. Sakina.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 147, No. 2, pp. 152-154, February, 2009

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Sakina, N.L., Golubkov, A.M., Smirnov, L.D. et al. Studying the Photoprotective Activity of a New Class of Heteroaromatic Antioxidants. Bull Exp Biol Med 147, 193–195 (2009). https://doi.org/10.1007/s10517-009-0472-8

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  • DOI: https://doi.org/10.1007/s10517-009-0472-8

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