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Granulomatous Inflammation in the Lungs of Mice with Systemic Candidiasis Receiving a Composition of Amphotericin B and Dialdehyde Dextran

  • Morphology and Pathomorphology
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Bulletin of Experimental Biology and Medicine Aims and scope

A composition of amphotericin B and dialdehyde dextran was used for the therapy of male C57Bl/6 mice with systemic candidiasis. The composition was more effective than free amphotericin B. A decrease in the number and size of candidal granulomas in the lungs was more significant after therapy with the study composition (compared to free amphotericin B).

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Authors and Affiliations

  1. Research Center of Clinical and Experimental Medicine, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia

    V. A. Shkurupiy & A. P. Nadeev

  2. Novosibirsk State Medical University, Russian Ministry of Health, Novosibirsk, Russia

    T. G. Chernova

Authors
  1. V. A. Shkurupiy
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  2. T. G. Chernova
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  3. A. P. Nadeev
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Corresponding author

Correspondence to A. P. Nadeev.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Suppl. 1, pp. 80–82, 2008

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Shkurupiy, V.A., Chernova, T.G. & Nadeev, A.P. Granulomatous Inflammation in the Lungs of Mice with Systemic Candidiasis Receiving a Composition of Amphotericin B and Dialdehyde Dextran. Bull Exp Biol Med 146, 829–831 (2008). https://doi.org/10.1007/s10517-009-0410-9

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  • DOI: https://doi.org/10.1007/s10517-009-0410-9

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