Taurine had the hypoglycemic effect during experimental insulin-dependent diabetes mellitus and decreased the concentrations of glucose and fructosamine, and increased the contents of insulin, C-peptide, and glycogen in the liver. Studying the dynamics of structural changes in pancreatic tissue confirmed a positive effect of taurine on β-cell function. The protective effect of taurine manifested in the absence of morphological signs for alloxan-induced diabetes: decrease in the number and size of pancreatic islets, change in their distribution, reduction of β-cell count, and accumulation of homogeneous deposits in islets.
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Translated from Byulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 146, No. 8, pp. 192–194, August, 2008
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Gavrovskaya, L.K., Ryzhova, O.V., Safonova, A.F. et al. Protective effect of taurine on rats with experimental insulin-dependent diabetes mellitus. Bull Exp Biol Med 146, 226–228 (2008). https://doi.org/10.1007/s10517-008-0258-4
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DOI: https://doi.org/10.1007/s10517-008-0258-4