Clinical and morphological comparison of wound healing after transplantation of living cultured allofibroblast on days 1–2 after the injury, collagen-1-based dressing with PDGF-BB, and traditional dressing with levomecol ointment showed that bioactive dressing accelerated wound epithelialization (5–7 days vs. 20–22 days with gauze dressing); the incidence of suppurative complications decreased, no crust formed, and epithelialization was not associated with the formation of a hypertrophic cicatrix. Biological dressing based on living cultured allofibroblasts and collagen-1 with PDGF-BB exhibited equal stimulatory effects on burn wound healing.
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Translated from Kletochnye Tehnologii v Biologii i Medicine, No. 3, pp. 166–170, August, 2008
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Ermolov, A.S., Smirnov, S.V., Khvatov, V.B. et al. The use of bioactive wound dressing, stimulating epithelial regeneration of IIIa-degree burn wounds. Bull Exp Biol Med 146, 153–157 (2008). https://doi.org/10.1007/s10517-008-0225-0
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DOI: https://doi.org/10.1007/s10517-008-0225-0