We studied the effect of xenogenic neonatal cardiomyocytes on enzymatic processes in rat myocardium under conditions of epinephrine-induced damage. It was found that transplantation of the cell preparation restricts the zone of suppressed enzyme activity in the myocardium and promotes its recovery. Less pronounced metabolic disturbances corresponded to less pronounced morphological changes in the myocardium.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Atherosclerosis and Cell Therapy. Ed. A. A. Runovich, J. I. Pivovarova, and T. E. Kurilskaya [in Russian], Irkutsk (2005).
Yu. N. Belenkov, F. T. Ageev, V. Yu. Mareev, et al., Serdechn. Nedostat., 4, No. 4, 168–173 (2003).
M. V. Bilenko, Ischemic and Reperfusion Damage to Organs [in Russian], Moscow (1989).
L. A. Bokeriya, Yu. I. Buazishvili, S. T. Matskeplishvili, et al., Kardiologiya, No. 9, 16–22 (2004).
A. S. Bushmelev, Serdechn. Nedostat., 3, No. 6, 318–321 (2003).
A. E. Vermel, Klin Med., 82, No. 1, 5–11 (2004).
P. F. Litvitskii, Pat. Fiziol. Eksp. Ter., No. 2, 2–12 (2002).
M. G. Pshennikova, Ibid., No. 4, 21–31 (2000).
V. I. Shumakov, E. N. Kazakov, N. A. Onishchenko, et al., Ros. Kardiol. Zh., No. 5, 42–50 (2003).
J. M. Hill, D. Orlic, and A. E. Arai, Circ. Res., 91, No. 12, 1092–1102 (2002).
Huang H.-Y., Huang Z., Hou J. et al., Acad. J. Second Mil. Univ., 25, No. 9, 950–955 (2004).
C. T. Mesquita, M. C. P. Pessoa, E. Perin, et al., Eur. J. Nucl. Med. Mol. Imag. 29, Suppl. 1, 226 (2002).
C. E. Murry, Acta Histochem. Cytochem., 35, No. 3, 210 (2002).
T. Ueno, T. Murohara, K. A. Robinson, et al., Boston Scientific Scimed, Inc. N 09/915853 (2005).
Z. M. Zhu, L. R. Gao, Y. X. Fei, Acad. J. Second Mil. Univ., 25, No. 9, 936–939 (2004).
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Kletochnye Tehnologii v Biologii i Medicine, No. 3, pp. 132–135, August, 2008
Rights and permissions
About this article
Cite this article
Bogorodskaya, S.L., Clinova, S.N., Mikashova, M.B. et al. Transplantation of xenogenic cardiomyocytes in experimental epinephrine-induced damage to myocardium: Enzyme activity and morphological parameters. Bull Exp Biol Med 146, 120–123 (2008). https://doi.org/10.1007/s10517-008-0218-z
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10517-008-0218-z