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Hyperviscosity syndrome in ovariectomized rats

Bulletin of Experimental Biology and Medicine volume 146, pages 92–95 (2008)Cite this article

Abstract

Ovariectomy reduces blood levels of sex hormones and considerably increases blood viscosity due to an increase in hematocrit and plasma fibrinogen content, disorders in viscoelastic characteristics of erythrocytes, and increase of their aggregation activity. Changes in the macrorheology are mainly responsible for the development of the hyperviscosity syndrome.

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Affiliations

  1. Institute of Pharmacology, Tomsk Research Center, Siberian Division of Russian Academy of Medical Sciences, Tomsk, Russia

    A. M. Plotnikova, O. I. Aliev & T. G. Borovskaya

  2. Siberian State Medical University, Tomsk, Russia

    Z. T. Shulgau & T. M. Plotnikova

Authors
  1. A. M. Plotnikova
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  2. Z. T. Shulgau
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  3. T. M. Plotnikova
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  4. O. I. Aliev
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  5. T. G. Borovskaya
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Corresponding author

Correspondence to T. M. Plotnikova.

Additional information

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Translated from Byulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 146, No. 7, pp. 101–104, July, 2008

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Plotnikova, A.M., Shulgau, Z.T., Plotnikova, T.M. et al. Hyperviscosity syndrome in ovariectomized rats. Bull Exp Biol Med 146, 92–95 (2008). https://doi.org/10.1007/s10517-008-0216-1

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  • DOI: https://doi.org/10.1007/s10517-008-0216-1

Key Words

  • ovariectomy
  • estrogens
  • hyperviscosity syndrome