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Evaluation of the expression of early activation marker CD69 by CD8+ lymphocytes in HIV-infected patients

  • Immunology and Microbiology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

We studied the expression of CD69 antigen on CD8+ lymphocytes in response to nonspecific activator phytohemagglutinin in 202 patients with HIV infection. It was found that the number of CD8+CD69+ lymphocytes in HIV-infected patients increased; this parameter negatively correlated with relative and absolute content of CD4+ cells and positively correlated with IgG concentration.

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Authors and Affiliations

  1. Krasnoyarsk State Medical Academy, Krasnoyarsk

    L. M. Kurtasova

  2. Regional Center on Prophylaxis and Combating of AIDS and Infection Diseases, Krasnoyarsk

    I. V. Isakov

Authors
  1. I. V. Isakov
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  2. L. M. Kurtasova
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Correspondence to L. M. Kurtasova.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 144, No. 12, pp. 661–663, December, 2007

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Isakov, I.V., Kurtasova, L.M. Evaluation of the expression of early activation marker CD69 by CD8+ lymphocytes in HIV-infected patients. Bull Exp Biol Med 144, 810–812 (2007). https://doi.org/10.1007/s10517-007-0437-8

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  • DOI: https://doi.org/10.1007/s10517-007-0437-8

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