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Effect of prenatal lead exposure on superoxide dismutase activity in the brain and liver of rat fetuses

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Abstract

Prenatal lead exposure had a damaging effect on Cu/Zn superoxide dismutase activity in the brain and liver of rat fetuses (20 days of gestation). The decrease in Cu/Zn superoxide dismutase activity in the brain and liver of treated fetuses reflects activation of free radical processes and impairment of the antioxidant defense system during prenatal lead exposure.

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Authors and Affiliations

  1. Moscow Institute of Psychiatry, Federal Agency for Health Care and Social Development, Moscow

    M. G. Uzbekov

  2. Research Center of Obstetrics, Gynecology, and Perinatology, Russian Medical Technologies, Moscow

    N. I. Bubnova & G. V. Kulikova

Authors
  1. M. G. Uzbekov
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  2. N. I. Bubnova
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  3. G. V. Kulikova
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Correspondence to M. G. Uzbekov.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 144, No. 12, pp. 632–634, December, 2007

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Uzbekov, M.G., Bubnova, N.I. & Kulikova, G.V. Effect of prenatal lead exposure on superoxide dismutase activity in the brain and liver of rat fetuses. Bull Exp Biol Med 144, 783–785 (2007). https://doi.org/10.1007/s10517-007-0431-1

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  • DOI: https://doi.org/10.1007/s10517-007-0431-1

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