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Comparative study of pharmacological activity of Afala on the model of hormone-induced prostatitis in rats

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Abstract

Afala (ultralow-dose antibodies to prostate-specific antigen) injected for 60 days to rats with hormone-induced prostatitis caused by sulpiride prevented the development of prostatic hyperplasia and reduced the severity of histological changes. The effect of Afala was superior to that of the reference drug (Serenoa repens extract).

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References

  1. G. G. Avtandilov, Medical Morphometry [in Russian], Moscow (1990).

  2. L. M. Gorilovskii, Benign Prostatic Hyperplasia [in Russian], Ed. N. A. Lopatkin, Moscow (1999), pp. 12–20.

  3. R. C. Bruskewitz, Rev. Urol., 5, No. 2, 72–80 (2003).

    PubMed  Google Scholar 

  4. V. F. Coppenolle, C. Slomianny, F. Carpentier, et al., Am. J. Physiol. Endocrinol. Metab., 280, 120–129 (2001).

    Google Scholar 

  5. F. C. Lowe, C. G. Roehrborn, C. Robertson, and P. Boyle, J. Urol., 159, No. 2, 257 (1998).

    Google Scholar 

  6. M. Paubert-Braquet, J. P. Raynaud, P. Braquet, et al., Pharmacol. Res., 31, Suppl., 31–35 (1995).

    Google Scholar 

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Correspondence to K. V. Savelieva.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 144, No. 11, pp. 542–544, November, 2007

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Savelieva, K.V., Borovskaya, T.G., Kheyfets, I.A. et al. Comparative study of pharmacological activity of Afala on the model of hormone-induced prostatitis in rats. Bull Exp Biol Med 144, 699–701 (2007). https://doi.org/10.1007/s10517-007-0409-z

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  • DOI: https://doi.org/10.1007/s10517-007-0409-z

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