Skip to main content
Log in

Use of lipid-modulating drugs in complicated course of coronary heart disease

  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

We present the results of the study of lipid-modulating drugs (pravastatin, atorvastatin, simvastatin, and fibrate gemfibrozil) in complicated coronary heart disease (acute coronary syndrome without ST elevation, chronic heart failure. In acute coronary syndrome statins produced a positive effect on some studied parameters, while in heart failure only the safety of short-term therapy with statins was demonstrated.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. N. A. Vaulin and N. A. Gratsianskii, Kardiologiya, 41, No. 11, 4–10 (2001).

    Google Scholar 

  2. N. A. Vaulin, N. A. Gratsianskii, N. N. Slavina, and O. V. Averkov, Ibid., 39, No. 8, 42–52 (1999).

    Google Scholar 

  3. N. A. Vaulin, N. A. Gratsianskii, I. S. Yavelov, and O. V. Averkov, Ibid., 41, No. 5, 4–8 (2001).

    Google Scholar 

  4. E. V. Pokrovskaya, N. A. Vaulin, N. A. Gratsianskii, et al., Ibid., 43, No. 1, 7–18 (2003).

    Google Scholar 

  5. E. V. Pokrovskaya, N. A. Gratsianskii, O. V. Averkov, et al., Ibid., No. 6, pp. 4–13.

    Google Scholar 

  6. E. V. Pokrovskaya, N. A. Gratsianskii, N. A. Vaulin, and A. D. Deev, Ibid., 44, No. 7, 40–45 (2004).

    Google Scholar 

  7. I. N. Smetanina, N. A. Vaulin, and N. A. Gratsianskii, Kardiologiya, 46, No. 5, 44–49 (2006).

    PubMed  CAS  Google Scholar 

  8. I. S. Anand, V. G. Florea, M. A. Kuskowski, et al., Eur. Heart J., 25, Suppl. 1, 245 (2004).

    Google Scholar 

  9. P. O. Bonetti, L. O. Lerman, C. Napoli, A. Lerman, Ibid., 24, No. 3, 225–248 (2003).

    Article  PubMed  CAS  Google Scholar 

  10. J. A. de Lemos, M. A. Blazing, S. D. Wiviott, et al., JAMA, 292, No. 11, 1307–1316 (2004).

    Article  PubMed  Google Scholar 

  11. H. Fukuta, D. C. Sane, S. Brucks, and W. C. Litte, Circulation, 112, No. 3, 357–363 (2005).

    Article  PubMed  CAS  Google Scholar 

  12. Heart Protection Study Collaborative Group et al., J. Am. Coll. Cardiol., 49, No. 3, 311–319 (2007).

    Article  CAS  Google Scholar 

  13. T. B. Horwich, R. MacLellan, and G. C. Fonarow, Ibid., 43, No. 4, 642–648 (2004).

    Article  PubMed  CAS  Google Scholar 

  14. H. Lee, W. Shi, P. Tontonoz, et al., Circ. Res., 87, No. 6, 516–521 (2000).

    PubMed  CAS  Google Scholar 

  15. P. Libby, Circulation, 104, No. 3, 365–372 (2001).

    PubMed  CAS  Google Scholar 

  16. G. Martin, H. Duez, C. Blanquart, et al., J. Clin. Invest., 107, No. 11, 1423–1432 (2001).

    Article  PubMed  CAS  Google Scholar 

  17. S. J. Robins, D. Collins, J. T. Wittes, et al., JAMA, 285, No. 12, 1585–1591 (2001).

    Article  PubMed  CAS  Google Scholar 

  18. G. G. Schwartz, A. G. Olsson, M. D. Ezekowitz, et al., JAMA, 285, No. 13, 1711–1718 (2001).

    Article  PubMed  CAS  Google Scholar 

  19. P. L. Thompson, I. Meredith, J. Amerena, et al. Am. Heart J., 148, No. 1, e2 (2004).

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

__________

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Supplement 2, pp. 67–75, April, 2007

Rights and permissions

Reprints and permissions

About this article

Cite this article

Gratsianskii, N.A., Vaulin, N.A. Use of lipid-modulating drugs in complicated course of coronary heart disease. Bull Exp Biol Med 144, 438–446 (2007). https://doi.org/10.1007/s10517-007-0348-8

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10517-007-0348-8

Key Words

Navigation