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Chemiluminescence as a method for detection and study of free radicals in biological systems

Bulletin of Experimental Biology and Medicine volume 144, pages 390–396 (2007)Cite this article

Abstract

Chemiluminescence observed during LPO or reactions of nitric oxide and oxygen radicals and was named “ultraweak luminescence”. In the presence of chemiluminescence activators (luminol, lucigenin, rhodamine G, or coumarine C-525) the appearance of radicals is associated with intensive fluorescence; the registration of this fluorescence is widely used in biomedical and clinical studies.

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Authors and Affiliations

  1. Institute of Physicochemical Medicine, Federal Agency for Health Care and Social Development, Moscow

    Yu. A. Vladimirov

  2. Faculty of Fundamental Medicine, M. V. Lomonosov Moscow State University, Russia

    E. V. Proskurnina & D. Yu. Izmailov

Authors
  1. Yu. A. Vladimirov
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  2. E. V. Proskurnina
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  3. D. Yu. Izmailov
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Additional information

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Supplement 2, pp. 13–20, April, 2007

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Vladimirov, Y.A., Proskurnina, E.V. & Izmailov, D.Y. Chemiluminescence as a method for detection and study of free radicals in biological systems. Bull Exp Biol Med 144, 390–396 (2007). https://doi.org/10.1007/s10517-007-0340-3

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  • DOI: https://doi.org/10.1007/s10517-007-0340-3

Key Words

  • chemiluminescence
  • radicals
  • kinetics
  • disease
  • antioxidants