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Role of cholinoceptors recycling in short-term potentiation of cholinosensitivity of command neurons in edible snail

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Abstract

Exocytosis inhibitor Exo 1, dynamin inhibitory peptide (inhibitor of endocytosis), and colchicine disturb short-term potentiation of cholinosensitivity of defensive behavior command neurons in edible snail induced by rhythmic electrical orthodromic stimulation. We hypothesize that the short-term potentiation of cholinosensitivity in the extra-synaptic membrane develops due to incorporation of extra cholinoceptors into neuron plasmalemma as a result of enhanced recycling of the internalized cholinoceptors with participation of microtubules.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 144, No. 9, pp. 247–250, September, 2007

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Abramova, M.S., Makhnovskii, D.A. & Pivovarov, A.S. Role of cholinoceptors recycling in short-term potentiation of cholinosensitivity of command neurons in edible snail. Bull Exp Biol Med 144, 276–279 (2007). https://doi.org/10.1007/s10517-007-0309-2

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  • DOI: https://doi.org/10.1007/s10517-007-0309-2

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