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Effects of carovertin on the reaction of retinal pigmented epithelium and radial glia to bright light

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Abstract

Light exposure (6000 lux, 6 h) caused reactive changes in rat retinal pigmented epithelium and radial glia on day 1. Foci of lesions with virtually complete absence of the layers formed by neurosensory cells appeared on day 7. The number of destructively changed radial gliocytes in these foci was by one order of magnitude higher than in the control. Carovertin reduced destruction of pigmented epithelium and radial glia and reduced the area of lesion foci.

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Authors and Affiliations

  1. Department of Histology, Embryology, and Cytology, Siberian State Medical University, Russia

    S. V. Logvinov, E. Yu. Varakuta, A. A. Zhdankina, A. V. Potapov & E. P. Mikhulya

  2. Institute of Pharmacology, Tomsk Research Center, Siberian Division of Russian Academy of Medical Sciences, Tomsk

    M. B. Plotnikov

Authors
  1. S. V. Logvinov
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  2. M. B. Plotnikov
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  3. E. Yu. Varakuta
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  4. A. A. Zhdankina
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  5. A. V. Potapov
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  6. E. P. Mikhulya
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Correspondence to S. V. Logvinov.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 144, No. 7, pp. 112–114, July, 2007

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Logvinov, S.V., Plotnikov, M.B., Varakuta, E.Y. et al. Effects of carovertin on the reaction of retinal pigmented epithelium and radial glia to bright light. Bull Exp Biol Med 144, 100–102 (2007). https://doi.org/10.1007/s10517-007-0266-9

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  • DOI: https://doi.org/10.1007/s10517-007-0266-9

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