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Apoptosis of leukocytes as a marker of neutrophil-endotheliocyte interaction in coronary heart disease

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Abstract

We studied the mechanism of interaction of peripheral blood neutrophils with endothelial cells (expression of cell adhesion molecules and production of NO) and the role of neutrophil apoptosis in the development of endothelial dysfunction. The effects of mitochondrial dysfunction of neutrophils on the development of apoptosis of these cells after their interaction with endothelial cells were analyzed.

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Authors and Affiliations

  1. Department of Biochemistry with a Course of Medical Chemistry, Russia

    V. A. Shul’man, S. Yu. Nikulina, P. A. But’yanov & A. P. Kuskaev

  2. Department of Internal Diseases No. 1, Russia

    A. B. Salmina, L. V. Trufanova, A. A. Fursov & E. V. Bol’shakova

  3. Central Research Laboratory, Krasnoyarsk State Medical Academy, Federal Agency for Health Care and Social Development, Russia

    M. Yu. Kotlovskii

Authors
  1. A. B. Salmina
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  2. V. A. Shul’man
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  3. S. Yu. Nikulina
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  4. L. V. Trufanova
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  5. A. A. Fursov
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  6. P. A. But’yanov
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  7. A. P. Kuskaev
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  8. E. V. Bol’shakova
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  9. M. Yu. Kotlovskii
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Corresponding author

Correspondence to P. A. But’yanov.

Additional information

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 144, No. 7, pp. 42–44, July, 2007

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Salmina, A.B., Shul’man, V.A., Nikulina, S.Y. et al. Apoptosis of leukocytes as a marker of neutrophil-endotheliocyte interaction in coronary heart disease. Bull Exp Biol Med 144, 39–41 (2007). https://doi.org/10.1007/s10517-007-0248-y

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  • DOI: https://doi.org/10.1007/s10517-007-0248-y

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