Abstract
Chronic stress exposure produces a damaging effect on the myocardium and reduces its functional (inotropic) reserves. Citrocard (50 mg/kg) and fenibut (50 mg/kg) prevent stress effects: animals receiving these preparations demonstrate higher contraction and relaxation rates and higher left-ventricular pressure during functional tests (volume load and maximum isometric load).
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 144, No. 7, pp. 24–28, July, 2007
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Perfilova, V.N., Tyurenkov, I.N., Lebedeva, S.A. et al. Effect of citrocard on functional reserves of the heart under conditions of chronic stress. Bull Exp Biol Med 144, 21–25 (2007). https://doi.org/10.1007/s10517-007-0243-3
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DOI: https://doi.org/10.1007/s10517-007-0243-3