Abstract
Injection of 1-deamino-1-monocarb-arginine-vasotocin (0.05 µg/100 g body weight) to alert rats caused increased natriuresis, diuresis, and reabsorption of osmotically free water. Injection of furosemide (0.5 mg/100 g body weight) increased Na+ excretion and did not increase reabsorption of osmotically free water. 1-Deamino-1-monocarb-arginine-vasotocin in molar conversion increased natriuresis by almost 6×104 times more effectively than furosemide.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 143, No. 5, pp. 494–497, May, 2007
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Kanashkina, T.A., Shakhmatova, E.I. & Natochin, Y.V. Effects of 1-deamino-1-monocarb-arginine-vasotocin on sodium ion and water excretion by rat kidneys. Bull Exp Biol Med 143, 563–565 (2007). https://doi.org/10.1007/s10517-007-0180-1
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DOI: https://doi.org/10.1007/s10517-007-0180-1