Skip to main content
Log in

Selank and its metabolites maintain homeostasis in the gastric mucosa

  • Pharmacology and Toxicology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Antiulcer properties of a synthetic anxiolytic Selank and in vivo formed metabolites of this compound were studied on 3 experimental models of ulceration. The test peptides decreased the area of experimental gastric ulcers.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. I. P. Ashmarin, E. P. Karazeeva, L. A. Lyapina, and G. E. Samonina, Biokhimiya, 63, No. 2, 149–155 (1998).

    Google Scholar 

  2. S. E. Zhuikova, K. E. Badmaeva, and Z. V. Bakaeva, Izv. Ros. Akad. Nauk. Ser. Biol., No. 5, 585–588 (2004).

  3. Yu. A. Zolotarev, A. K. Dadayan, O. V. Dolotov, et al., Bioorgan. Khim., 32, No. 2, 80–88 (2006).

    Google Scholar 

  4. T. S. Pavlov and G. E. Samonina, Dokl. Akad. Nauk, 397, No. 4, 1–3 (2004).

    Google Scholar 

  5. T. S. Pavlov, L. Ts. Sanzhieva, G. E. Samonina, et al., Ros. Fiziol. Zh., 91, No. 2, 178–183 (2005).

    CAS  Google Scholar 

  6. S. B. Seredenin, M. M. Kozlovskaya, Yu. A. Blednov, et al., Zh. Vyssh. Nervn. Deyat., 48, No. 1, 153–159 (1998).

    CAS  Google Scholar 

  7. L. P. Filaretova, A. A. Filaretov, and G. B. Makara, Am. J. Physiol., 274, No. 6, Pt. 1, G1024–G1030 (1998).

  8. S. Okabe, J. L. Roth, and C. J. Pfeiffer, Am. J. Dig. Dis., 16, No. 3, 277–284 (1971).

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to G. E. Samonina.

Additional information

__________

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 143, No. 1, pp. 57–59, January, 2007

Rights and permissions

Reprints and permissions

About this article

Cite this article

Pavlov, T.S., Samonina, G.E., Bakaeva, Z.V. et al. Selank and its metabolites maintain homeostasis in the gastric mucosa. Bull Exp Biol Med 143, 51–53 (2007). https://doi.org/10.1007/s10517-007-0014-1

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10517-007-0014-1

Key Words

Navigation