Abstract
We studied the effects of plant extracts and products of their biological treatment on trans-sialidase activity in human blood plasma. Extracts of kelp, fucus, yarrow, Saint John’s wort, onion, and honey in vitro decreased trans-sialidase activity. Extracts of pollen (beebread) and garlic powder produced the maximum inhibitory effect. trans-Sialidase activity of blood plasma ex vivo decreased 2-fold after peroral administration of pollen and garlic powder. A correlation was found between the decrease in trans-sialidase activity in blood plasma and ability of blood plasma to induce cholesterol accumulation in cultured cells from the intact human aortic intima.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 143, No. 1, pp. 52–56, January, 2007
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Aksenov, D.V., Kaplun, V.V., Tertov, V.V. et al. Effect of plant extracts on trans-sialidase activity in human blood plasma. Bull Exp Biol Med 143, 46–50 (2007). https://doi.org/10.1007/s10517-007-0013-2
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DOI: https://doi.org/10.1007/s10517-007-0013-2