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Antiarrhythmic effect of heat adaptation in ischemic and reperfusion injury to the heart

  • General Pathology and Pathophysiology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Study on a model of 6-day dosed adaptation to heat in rats showed that this adaptation decreased the severity of cardiac arrhythmias during ischemic and reperfusion injury. The duration of arrhythmias decreased not only in the ischemic period, but also under conditions of reperfusion. Adaptation delayed the development of arrhythmias during ischemia, decreased the number of animals with late reperfusion arrhythmias, and improved recovery of the heart after ischemia and reperfusion.

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Correspondence to I. Yu. Malyshev.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 143, No. 1, pp. 13–16, January, 2007

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Monastyrskaya, E.A., Belkina, L.M., Manukhina, E.B. et al. Antiarrhythmic effect of heat adaptation in ischemic and reperfusion injury to the heart. Bull Exp Biol Med 143, 9–11 (2007). https://doi.org/10.1007/s10517-007-0003-4

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  • DOI: https://doi.org/10.1007/s10517-007-0003-4

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