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Rapid method for evaluation of cholinesterase inhibitors

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Abstract

The fluorescence intensity of reversible inhibitor ethidium bromide fluorophore complex with equine blood butyryl cholinesterase decreases in the presence of inhibitor (tacrine) not fluorescing in the visible spectrum. An express method for tacrine evaluation is developed.

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Correspondence to S. B. Ryzhikov.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 142, No. 11, pp. 591–593, November, 2006

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Gainullina, E.T., Klyuster, O.V., Ryzhikov, S.B. et al. Rapid method for evaluation of cholinesterase inhibitors. Bull Exp Biol Med 142, 643–645 (2006). https://doi.org/10.1007/s10517-006-0438-z

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  • DOI: https://doi.org/10.1007/s10517-006-0438-z

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