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Adaptive effects of dexamethasone in stress exposure

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Abstract

Disorders in the compensatory adaptive processes underlie the development of many somatic diseases. The neuroimmunoendocrine complex and one of its main components, the hypothalamic—pituitary—adrenal system, play the leading role in the maintenance of the adaptation reserve. Treatment with a synthetic analog of hydrocortisone (final effector of this system) in low doses modulates its function by inducing positive changes in the adaptive mechanisms under conditions of stress exposure.

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Authors and Affiliations

  1. Institute of Pharmacology, Tomsk Research Center, Siberian Division of Russian Academy of Medical Sciences, Russia

    V. V. Udut, G. A. Popova & E. V. Borodulina

Authors
  1. V. V. Udut
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  2. G. A. Popova
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  3. E. V. Borodulina
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Correspondence to V. V. Udut.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 142, No. 11, pp. 528–531, November, 2006

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Udut, V.V., Popova, G.A. & Borodulina, E.V. Adaptive effects of dexamethasone in stress exposure. Bull Exp Biol Med 142, 583–586 (2006). https://doi.org/10.1007/s10517-006-0424-5

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  • DOI: https://doi.org/10.1007/s10517-006-0424-5

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