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Cell microvesicles during experimental endotoxemia

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Abstract

The dynamics of microvesicle formation in arterial blood in generalized Schwartzman phenomenon was studied. Successive (with 24-h interval) intravenous injections of endotoxin to rabbits in a dose of 1 mg/kg and 3 mg/kg caused an increase in the content of microvesicles in the blood, some of them containing ecto-5′-nucleotidase. Biphasic changes in arterial blood clotting time and erythrocyte hemolysis were observed.

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Authors and Affiliations

  1. Department of Biochemistry, Kazan State Medical University, Kazan

    L. D. Zubairova, D. M. Zubairov, I. A. Andrushko, G. Yu. Svintenok & I. G. Mustafin

Authors
  1. L. D. Zubairova
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  2. D. M. Zubairov
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  3. I. A. Andrushko
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  4. G. Yu. Svintenok
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  5. I. G. Mustafin
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Corresponding author

Correspondence to L. D. Zubairova.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 142, No. 11, pp. 517–520, November, 2006

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Zubairova, L.D., Zubairov, D.M., Andrushko, I.A. et al. Cell microvesicles during experimental endotoxemia. Bull Exp Biol Med 142, 573–576 (2006). https://doi.org/10.1007/s10517-006-0421-8

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  • DOI: https://doi.org/10.1007/s10517-006-0421-8

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