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Homocysteine toxicity in organotypic cultures of rat retina

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Abstract

Effects of homocysteine in toxic concentrations on retinal neurons were studied in vitro. In organotypic roller cultures of postnatal (8–12-day-old) and adult rat retina homocysteine caused multiple damage to neurons in the outer nuclear layer, in deep compartments of the inner nuclear layer, and ganglion cell layer.

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Authors and Affiliations

  1. Laboratory of Experimental Neurocytology, Institute of Brain Research, Russian Academy of Medical Sciences, Moscow

    I. V. Viktorov, O. P. Aleksandrova & N. Yu. Alekseeva

Authors
  1. I. V. Viktorov
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  2. O. P. Aleksandrova
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  3. N. Yu. Alekseeva
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Correspondence to I. V. Viktorov.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 141, No. 4, pp. 458–461, April, 2006

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Viktorov, I.V., Aleksandrova, O.P. & Alekseeva, N.Y. Homocysteine toxicity in organotypic cultures of rat retina. Bull Exp Biol Med 141, 471–474 (2006). https://doi.org/10.1007/s10517-006-0202-4

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  • DOI: https://doi.org/10.1007/s10517-006-0202-4

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