Skip to main content
SpringerLink
Log in

Morphochemical study of hippocampus of August rats after systemic treatment with amphetamine followed by injection of delta sleep-inducing peptide

  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Quantitative interferometry showed that chronic amphetamine administration to August rats (2.5 mg/kg/day for 3 weeks) increased the area of neuronal cytoplasm and nuclei and content and concentrations of proteins in hippocampal CA3 neurons. These changes persisted after single injection of delta sleep-inducing peptide (60 µg/kg). The reaction of the entire neuronal population of hippocampal CA3 neurons to amphetamine is similar.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. V. Ya. Brodskii, Cell Trophics [in Russian], Moscow (1966).

  2. I. V. Viktorov, Modern Methods for Morphological Studies [in Russian], Moscow (1966), pp. 7–10.

  3. L. M. Gershtein, Tsitologiya, 21, No. 4, 424–428 (1979).

    CAS  Google Scholar 

  4. V. G. Kolpakov, Catatonia in Animals [in Russian], Novosibirsk (1990).

  5. V. N. Mats and O. L. Segal, Neurochemical Bases of Training and Memory [in Russian], Moscow (1989), pp. 135–155.

  6. N. S. Popova and E. L. Dovedova, Ros. Fiziol. Zh., 84, Nos. 1–2, 24–29 (1998).

    CAS  Google Scholar 

  7. R. M. Salieva, E. V. Koplik, Z. A. Kamenov, and A. B. Poletaev, Byull. Eksp. Biol. Med., No. 10, 464–466 (1989).

  8. K. V. Sudakov, Zh. Vyssh. Nervn. Deyat., 37, No. 1, 78–87 (1987).

    CAS  Google Scholar 

  9. K. V. Sudakov, Individual Resistance to Mental Stress [in Russian], Ryazan (1998).

  10. E. M. Khvatova, N. A. Rubanova, I. A. Prudchenko, and I. I. Mikhaleva, Progress in Functional Neurochemistry [in Russian], St. Petersburg (2003), pp. 120–126.

Download references

Author information

Authors and Affiliations

  1. Laboratory of Brain Ultrastructure and Cytochemistry, Institute of Brain, Russian Academy of Medical Sciences, Moscow

    L. M. Gershtein, A. V. Sergutina & V. I. Rakhmanova

Authors
  1. L. M. Gershtein
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. V. Sergutina
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. V. I. Rakhmanova
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to L. M. Gershtein.

Additional information

__________

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 141, No. 4, pp. 455–457, April, 2006

Rights and permissions

Reprints and permissions

About this article

Cite this article

Gershtein, L.M., Sergutina, A.V. & Rakhmanova, V.I. Morphochemical study of hippocampus of August rats after systemic treatment with amphetamine followed by injection of delta sleep-inducing peptide. Bull Exp Biol Med 141, 468–470 (2006). https://doi.org/10.1007/s10517-006-0201-5

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10517-006-0201-5

Key Words

Search

Navigation