Skip to main content
Log in

Antiamnesic effect of combined treatment with galantamine and estradiol in middle-aged ovariectomized female rats

  • Pharmacology and Toxicology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The effect of chronic combined treatment with galantamine and 17β-estradiol on passive avoidance retention was studied in middle-aged ovariectomized female rats (15 months) with scopolamine-induced amnesia. Combined treatment with galantamine and estradiol completely restored retrieval of memory traces in middle-aged ovariectomized female rats.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Ya. Buresh, O. Bureshova, and J. P. Houston, Methods and Main Experiments in Studies of the Brain and Behavior [in Russian], Moscow (1991).

  2. Ya. D. Kirshenblat, Practicum on Endocrinology [in Russian], Moscow (1969).

  3. T. Backstrom, Ciba Found. Symp., 191, 171–186 (1995).

    PubMed  CAS  Google Scholar 

  4. R. B. Gibbs, Brain Res., 757, No. 1, 10–16 (1997).

    Article  PubMed  CAS  Google Scholar 

  5. R. B. Gibbs, A. Hashash, and D. A. Johnson, Ibid., 749, No. 1, 143–146 (1997).

    Article  PubMed  CAS  Google Scholar 

  6. V. W. Henderson, A. Paganini-Hill, C. K. Emanuel, et al., Arch. Neurol., 51, No. 9, 896–900 (1994).

    PubMed  CAS  Google Scholar 

  7. J. W. Simpkins, F. S. Green, K. E. Griedley, et al., Am. J. Med., 103, No. 3A, 19S–25S (1997).

    Article  PubMed  CAS  Google Scholar 

  8. M. Singh, E. M. Meyer, W. J. Millard, and J. W. Simpkins, Brain Res., 644, No. 2, 305–312 (1994).

    Article  PubMed  CAS  Google Scholar 

  9. M. Singh, E. M. Meyer, and J. W. Simpkins, Endocrinology, 136, No. 5, 2320–2324 (1995).

    Article  PubMed  CAS  Google Scholar 

  10. W. J. Wilson and J. A. Cook, Acta Neurobiol. Exp. (Wars.), 54, No. 4, 377–391 (1994).

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

__________

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 141, No. 4, pp. 411–413, April, 2006

Rights and permissions

Reprints and permissions

About this article

Cite this article

Losev, N.A., Fedotova, Y.O. & Sapronov, N.S. Antiamnesic effect of combined treatment with galantamine and estradiol in middle-aged ovariectomized female rats. Bull Exp Biol Med 141, 427–429 (2006). https://doi.org/10.1007/s10517-006-0190-4

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10517-006-0190-4

Key Words

Navigation