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Study of pathogenesis of ventricular arrhythmia in experimental rats by separation of sinus and ventricular substitutional rhythms

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Abstract

Pathogenesis of cardiac arrhythmia was determined by EEC changes after ATP-induced complete atrioventricular block. The re-entry mechanism underlays extrasystoles with equal coupling intervals with complexes of ventricular substitution rhythms, which transformed into paroxysmal tachycardia with equal R—R intervals, ventricular flutter, and ventricular fibrillation. Ectopic automaticity was characterized by extrasystole unrelated to the complexes of substitutional rhythms, which was transformed into accelerated idioventricular rhythm and asystole. During trigger activity, the extrasystoles were associated with complexes of basic rhythm and transformed themselves into torsades de pointes and ventricular fibrillation.

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Authors and Affiliations

  1. Vinnitsa National University of Medicine, Ukraine

    V. M. Moroz & T. N. Lipnitskii

Authors
  1. V. M. Moroz
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  2. T. N. Lipnitskii
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 141, No. 4, pp. 382–385, April, 2006

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Moroz, V.M., Lipnitskii, T.N. Study of pathogenesis of ventricular arrhythmia in experimental rats by separation of sinus and ventricular substitutional rhythms. Bull Exp Biol Med 141, 400–403 (2006). https://doi.org/10.1007/s10517-006-0182-4

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  • DOI: https://doi.org/10.1007/s10517-006-0182-4

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