Skip to main content
SpringerLink
Log in

Prooxidant-antioxidant state of the organism during oxidative stress and correction of the L-arginine-NO system

  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The prooxidant-antioxidant balance in rats with oxidative stress was studied during correction of the L-arginine-NO system. Oxidative stress was induced by intravenous injection of E. coli lipopolysaccharide. Under conditions of oxidative stress the prooxidant-antioxidant imbalance was least pronounced during selective correction of the L-arginine-NO system. L-Arginine and nonselective NO synthase inhibitor had little protective effect.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. N. K. Zenkov, V. Z. Lankin, and E. B. Men’shchikova, Oxidative Stress. Biochemical and Pathophysiological Aspects [in Russian], Moscow (2001).

  2. O. I. Aruoma and S. L. Cuppett, Antioxidant Methodology: in Vivo and in Vitro Concepts, New York (1997).

  3. A. Berges, L. Van Nassauw, J. Bosmans, et al., Acta Cardiol., 58, No. 2, 119–132 (2003).

    Article  PubMed  Google Scholar 

  4. B. Brune, J. Zhou, and A. von Knethen, Kidney Int. Suppl., No. 84, S22–S24 (2003).

  5. L. Connelly, M. Palacios-Callender, C. Ameixa, et al., J. Immunol., 166, No. 6, 3873–3881 (2001).

    PubMed  CAS  Google Scholar 

  6. L. G. Fisher, D. J. Horstman, K. Hahnenkamp, et al., Anesthesiology, 91, No. 6, 1724–1732 (1999).

    Article  Google Scholar 

  7. C. A. Rice-Evans, A. T. Diplock, and M. C. R. Symons, Laboratory Techniques in Biochemistry and Molecular Biology: Techniques in Free Radical Research, London (1991).

  8. C. Zhang, L. M. Walker, J. A. Hinson, and P. R. Mayeux, J. Pharmacol. Exp. Ther., 293, No. 3, 968–972 (2000).

    PubMed  CAS  Google Scholar 

  9. V. V. Zinchuk and L. V. Dorokhina, Nitric Oxide, 6, No. 1, 29–34 (2002).

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Normal Physiology, Grodno Medical University, Belarus

    A. N. Glebov & V. V. Zinchuk

Authors
  1. A. N. Glebov
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. V. V. Zinchuk
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to V. V. Zinchuk.

Additional information

__________

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 141, No. 4, pp. 368–370, April, 2006

Rights and permissions

Reprints and permissions

About this article

Cite this article

Glebov, A.N., Zinchuk, V.V. Prooxidant-antioxidant state of the organism during oxidative stress and correction of the L-arginine-NO system. Bull Exp Biol Med 141, 387–389 (2006). https://doi.org/10.1007/s10517-006-0178-0

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10517-006-0178-0

Key Words

Search

Navigation